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KMID : 0880220110490010161
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Journal of Microbiology
2011 Volume.49 No. 1 p.161 ~ p.164
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Antimicrobial effect of Korean propolis against the mutans streptococci isolated from Korean
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Kim Min-Jung
Kim Chun-Sung
Kim Byung-Hoon
Ro Sang-Bok
Lim Yun-Kyong
Park Soon-Nang
Cho En-gene
Ko Jang-Hyuk
Kwon Soon-Sung
Ko Yeong-Mu
Kook Joong-Ki
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Abstract
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The aim of this study was to determine the optimal concentration of Korean propolis against clinical isolates of mutans streptococci (MS) from Koreans. The antimicrobial activity was evaluated using the minimum inhibitory concentration (MIC) and time-kill curves against mutans streptococci. The MIC90 values of propolis for MS were 35 μg/ml. Propolis had a bacteriostatic effect on Streptococcus mutans ATCC 25175T and bactericidal effects on Streptococcus sobrinus ATCC 33478T at > 2×MIC (70 μg/ml). These results suggest that the propolis can be used in the development of oral hygiene products for the prevention of dental caries.
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KEYWORD
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antimicrobial effect, propolis, mutans streptococci, Koreans
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